Important publications

Abd Alla, J., Langer, A., Wolf, S., Fu X, Rageh MA, Quitterer U. BBLN triggers CAMK2D pathology in mice under cardiac pressure overload and potentially in unrepaired hearts with tetralogy of Fallot. external page Nat Cardiovasc Res 2023; 2:1044–1059.

Abd Alla J, Nerger E, Langer A, Quitterer U. Identification of membrane palmitoylated protein 1 (MPP1) as a heart-failure-promoting protein triggered by cardiovascular risk factors and aging. external page Biochem Pharmacol. 2023;217:115789.

Quitterer U, AbdAlla S.
Pathological AT1R-B2R Protein Aggregation and Preeclampsia. external page Cells. 2021; 10(10):2609.

Abd Alla J, Jamous YF, Quitterer U.
Stearoyl-CoA Desaturase (SCD) Induces Cardiac Dysfunction with Cardiac Lipid Overload and Angiotensin II AT1 Receptor Protein Up-Regulation. external page Int J Mol Sci. 2021 Sep 13;22(18):9883.

Quitterer U, AbdAlla S.
Discovery of Pathologic GPCR Aggregation. external page Front Med (Lausanne). 2019 Jan 30;6:9.

Wolf S, Abd Alla J, Quitterer U.
Sensitization of the Angiotensin II AT1 Receptor Contributes to RKIP-Induced Symptoms of Heart Failure. external page Front Med (Lausanne). 2019 Jan 9;5:359.

Quitterer U, Fu X, Pohl A, Bayoumy KM, Langer A, AbdAlla S.
Beta-Arrestin1 Prevents Preeclampsia by Downregulation of Mechanosensitive AT1-B2 Receptor Heteromers.
external page Cell. 2019 Jan 10;176(1-2):318-333.

AbdAlla S, El Hakim A, Abdelbaset A, Elfaramawy Y, Quitterer U.
Inhibition of ACE Retards Tau Hyperphosphorylation and Signs of Neuronal Degeneration in Aged Rats Subjected to Chronic Mild Stress. external page Biomed Res Int. 2015;2015:917156.

Abd Alla J, Graemer M, Fu X, Quitterer U.
Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. external page J Biol Chem. 2016 Feb 5;291(6):2583-600.

Quitterer U, AbdAlla S.
Vasopressor meets vasodepressor: The AT1-B2 receptor heterodimer. external page Biochem. Pharmacol. 2014, 88, 284-290.

Fu X, Koller S, Abd Alla J, Quitterer U.
Inhibition of G-protein-coupled receptor kinase 2 (GRK2) triggers the growth-promoting mitogen-activated protein kinase (MAPK) pathway. external page J. Biol. Chem. 2013, 288, 7738-7755. external page GEO accession no. GSE42753, external page GEO accession no. GSE42771

Abdalla J, Langer A, Elzahwy SS, Arman-Kalcek G, Streichert T, Quitterer U.
Angiotensin-converting enzyme (ACE) inhibition down regulates the pro-atherogenic chemokine receptor 9 (CCR9) - chemokine ligand 25 (CCL25) axis. external page J. Biol. Chem., 2010, 285, 23496-23505. external page GEO accession no. GSE19286

• external page Selected by NCBI as GEO profile (GDS3683) with presentation on 2256 pages
• http://www.ncbi.nlm.nih.gov/geoprofiles?term=GDS3683[ACCN]

AbdAlla S, Lother H, Langer A, el Faramawy Y, Quitterer U.
Factor XIIIA transglutaminase crosslinks AT1 receptor dimers of monocytes at the onset of atherosclerosis. external page Cell, 2004, 119, 343-354.

• Preview: Ogawa S, Glass CK. external page Factor XIIIA (cross)links AT1 receptors to atherosclerosis. Cell, 2004, 119, 313-314.
• Commentary: Thomas WG. external page Double trouble for type 1 angiotensin receptors in atherosclerosis. New. Engl. J. Med., 2005, 352, 506-508.
• Data added to the "Biomolecular Interaction Network Database" (BIND)

Lorenz K, Lohse MJ, Quitterer U.
PKC switches the Raf kinase inhibitor from Raf-1 to GRK-2. external page Nature, 2003, 426, 574-579.

• Commentary: Goel, R., Baldassare, J. J. external page Killing two birds with one RKIP. Trends. Endocrinol. Metab., 2004, 15, 91-92.
• Data added to the "Biomolecular Interaction Network Database" (BIND)

AbdAlla S, Lother H, Massiery A, Quitterer U.
Increased AT1 receptor heterodimers in preeclampsia mediate enhanced angiotensin II responsiveness. external page Nature Medicine, 2001, 7, 1003-1009.

• News and Views: Lodwick D. external page Receptor double-trouble in preeclampsia. Nature Medicine, 2001, 7, 999-1000.
• 2013: Independent confirmation of AT1-receptor heterodimers after 10 years of discussion: external page Wilson et al. J. Biol. Chem., 2013, 288, 18872-18884.

AbdAlla S, Lother H, Quitterer U.
AT1-receptor heterodimers show enhanced G-protein activation and altered receptor sequestration. external page Nature, 2000, 407, 94-98.

• Highly cited paper (Top 1 % of the field according to ISI Web of Science)
• 2013: Independent confirmation of AT1-receptor heterodimers after 10 years of discussion: external page Wilson et al. J. Biol. Chem., 2013, 288, 18872-18884.